Chronic Conditions & Health

Our goal is to understand causes and consequences of chronic conditions (discovery science), to test if interventions improve health among people with chronic conditions (evaluation science), and to assess ways to implement these findings into real-world programs and policy (implementation science).

 

  ocre  Discovery Science              ocre   Evaluation Science              blue  Implementation Science

 

A multicenter, observational cohort to study the characteristics of individuals asking for pre-exposure prophylaxis (PrEP) and the incidence of HIV and STIs: «The Swiss PrEPared Study»

Jan Fehr / Benjamin Hampel

ocre

The SwissPrEPared Study aims to identify the characteristics of individuals asking for pre-exposure prophylaxis (PrEP) and monitor the incidence of HIV and other sexually transmitted infections.

More…

 

Accompanying scientific study to the implementation of the “Living well with COPD” program (SELFIS-2)

Anja Frei

ocre blue

This project aims to assess the effectiveness (level of patients) and the implementation (focus on optimization of the program) of the “Living well with COPD” self-management program, implemented throughout Switzerland by Cantonal Lung Associations.

More…

 

An implementation evaluation of a home-based exercise intervention for COPD patients

Anja Frei

ocre blue

This study aims to make the connection from science to practice in the context of the HOMEX intervention targeting patients with chronic obstructive pulmonary disease (COPD).

More…

 

AMIS Plus:  National Registry
of Acute Myocardial Infarction
in Switzerland

Dragana Radovanovic

ocre

The AMIS Plus (Acute myocardial Infarction in Switzerland) project is a national registry for patients with acute coronary syndrome (unstable angina and  myocardial infarction).

More…

 

C-SURF: Cohort Study on Substance use risk factors

Leonhard Held

ocre

The C-SURF cohort study examines the patterns of substance use and risk factors among young Swiss men over time.

More…

 
 

Cancer incidence in the
Cantons of Zurich & Zug (Cancer Registries)

Sabine Rohrmann

ocre blue

This project registers patients with newly detected cancer in the cantons of Zurich and Zug in order to compute incidence rates of cancer.

More…

 
 

Characterization of prevalence, type, treatment, burden of disease and predictors of respiratory symptoms in very prematurely born children in the Zurich area (FLiP)

Susi Kriemler

ocre

The aim of this project is to assess the long-term consequences of very premature birth on respiratory health.

More…

 

Chronic Obstructive Pulmonary Disease (COPD) Prediction Models

Milo Puhan

ocre  ocre

Our study develops COPD disease severity indices that better represent the clinical manifestations of COPD and their prognostic implications.

More…

 

Cochrane Public Health Europe

Margot Mütsch /
Milo Puhan

ocre blue

As a Cochrane Public Health Europe satellite, our overall aim is to support the dissemination and use of public health evidence by public health decision makers. 

More…

 

Comparison of two commercially available devices to measure nitric oxide lung diffusing capacity in healthy, non-smoking adults

Thomas Radtke

ocre

 

This study compares two commercially available devices that measure nitric oxide lung diffusing capacity (DLNO) in healthy adults.

More…

 

Cultural diversity and modifiable risk factors of chronic disease

Matthias Bopp

ocre

This project examines risk factors of chronic conditions and possibilities for improving health behavior in Switzerland.

More…

 
 

Digital Health Innovation: a Governance Roadmap for Switzerland (D-GOVmap)

Milo Puhan

blue

This project aims to produce a national policy roadmap for digital health innovation in Switzerland

More…

 

Does cardiopulmonary exercise testing provide short-term prognostic information in advanced cystic fibrosis lung disease?

Thomas Radtke /
Helge Hebestreit

ocre

The aim of this international multi-centre study is to determine the prognostic value of cardiopulmonary exercise testing as predictor of short-term death and/or lung transplantation in advanced cystic fibrosis lung disease.

More…

 

FLISbook - How are people at increased risk during the Corona pandemic?

Viktor von Wyl

blue

The corona pandemic continues to affect our lives. How do people with increased risks feel about it?

More…

 

GDM – Gestational Diabetes Mellitus in HIV-infected Women
George Abongomera

Sabine Haller

ocre blue

This observational study aims to establish a diabetes screening program for Gestational diabetes mellitus (GDM) at the Prevention, Treatment & Care Unit of the Infectious Diseases Institute (IDI) in Kampala, Uganda and ultimately aims to obtain epidemiological data on the prevalence of GDM in HIV positive women.

More…

 

Geographic variation in the utilisation of health care interventions: what is the role of recommendations and other influences?
Matthias Schwenkglenks

ocre blue

We study geographic variation in the healthcare for chronic diseases, related determinant with a special focus on clinical recommendations, and  consequences.

More…

 

Health economic aspects of atrial fibrillation: analyses based on the Swiss-AF cohort study

Matthias Schwenkglenks

ocre

We study the cost implications of atrial fibrilation, a frequent heart arrhythmia, and the value-for-money of related treatments, based on data from the Swiss Atrial Fibrillation Cohort Study.

More…

 

Holistic and patient-centered triage: Redesigning COPD-management in primary care

Sarah Ziegler / Milo Puhan

ocre blue

The primary aim of our project is to design a triage intervention at the point of primary care to provide palliative care support to COPD patients and their families depending on their COPD-related burden of suffering

More…

 

HOMEX: Home-based exercise training for COPD patients.

Anja Frei

ocre ocre

 In the two trials HOMEX 1 and HOMEX 2, we evaluate the effectiveness of a
long-term home-based exercise training program using minimal equipment vs. usual care in patients with COPD. 

More…

 

Long Covid in Military Organisations (LoCoMo)

Pat Schlagenhauf

ocre

The  “LoCoMo” study is a prospective, longitudinal cohort study designed to follow-up on 500 tested army personnel who tested either SARS-CoV-2 positive or negative while serving in the Swiss Armed Forces in early 2020.

More…

 

M-HEALTH

Oliver Gruebner

ocre ocre

We work on providing big geo- social media data that will allow studies on health and social behaviour monitoring

Mehr…

 

Mental health,
vulnerability and infections

Vladeta Ajdacic /
Margot Mütsch

ocre

This project explores the associations between mental health, atopies, chronic inflammatory diseases and infections.

More…

 
 

Mobile apps to use against the coronavirus pandemic

Viktor von Wyl

blue

What are the benefits of new apps in the context of the Corona pandemic? We develop the methodological basis for their classification and evaluation.

More…

 

Mobilise-D: Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

Milo Puhan

ocre

The European Innovative Medicines Initiatives funded Mobilise-D project aims to develop and implement a digital mobility assessment solution to demonstrate that real-world digital mobility outcomes can successfully predict relevant clinical outcomes and to validate these outcomes in different patient populations.

More…

 

Nationale Studie
onkologische Rehabilitation

Sabine Rohrmann

ocre  ocre

Erarbeitung einer systematischen Literaturübersicht und einer Erhebung der ambulanten onkologischen Rehabilitation in der Schweiz.

More…

 

Patient Preferences Regarding Benefits and Harms of Advanced Prostate Cancer Treatments in Switzerland

Milo Puhan / Dominik Menges

ocre

We elicit patient preferences regarding the expected benefits and potential harms of the available treatment options in the context of advanced prostate cancer, and explore differences in patient preferences between important population subgroups.

More…

 

Predictors of long-term work participation among patients with cystic fibrosis undergoing lung transplantation

Thomas Radtke

ocre

The aim of this retrospective study is to assess predictors of long-term work participation among lung transplant recipients with cystic fibrosis.

More…

 

SELFIS project: Implementation evaluation of the LWWCOPD program

Milo Puhan

ocre blue

With the SELFIS study we evaluate the implementation of the “Living well with COPD“ self-management program by Cantonal Lung Associations in their already existing offers of preventive and therapeutic services.

More…

 

SURFit: Effects of a 1-year partially supervised exercise programme in childhood cancer survivors – a randomized controlled trial

Susi Kriemler

ocre ocre

We test the effect of a 12-mt partially supervised conditioning program in childhood cancer survivors by a randomized controlled trial.

More…

 
 

Swiss Atrial Fibrillation Cohort 

Matthias Schwenkglenks

ocre blue

We collect prospective health economic data for the Swiss-Atrial Fibrillation (AF) cohort, a cohort study of Swiss AF patients.

More…

 

 
 

SwissDEM

Anja Frei / Milo Puhan

ocre

The SwissDEM study aims to assess the health condition of elderly people (≥65 years) to ascertain how many people in Switzerland are affected by dementia and how the Corona pandemic affects mental health in this specific age group.

More…

 

Swiss MS Registry

Viktor von Wyl

ocre ocre blue

The Swiss MS Registry is a patient-centered, national research database that aims to comprehensively document aspects of MS that can impact an affected  person's daily live, including social and medical data.

More…

 

Swiss Youth Epidemiological Study on Mental Health (S-YESMH)

Meichun Mohler-Kuo

ocre

The S-YESMH study updates prevalence estimates for major mental disorders, assesses help-seeking behaviors, estimates potential untreated rates, and identifies factors associated with mental illness among Swiss youth.

More…

 
 

The prediction of cause-specific and overall mortality by co-morbidities in a registry-based cohort of colorectal cancer patients.

Sabine Rohrmann

ocre

We examine the association between co-morbidities at the time of cancer diagnosis and survival in patients with colorectal cancer.

More… 

 

 

 
 

Zurich Health Policy Center

Margot Mütsch / Milo Puhan / Sibylle Brunner

blue

The Zurich Health Policy Center contributes to the translation, dissemination and implementation of evidence into practice.

More…