Chronic Conditions & Health

Our goal is to understand causes and consequences of chronic conditions (discovery science), to test if interventions improve health among people with chronic conditions (evaluation science), and to assess ways to implement these findings into real-world programs and policy (implementation science).

 

  ocre  Discovery Science              ocre   Evaluation Science              blue  Implementation Science

 

A multicenter, observational cohort to study the characteristics of individuals asking for pre-exposure prophylaxis (PrEP) and the incidence of HIV and STIs: «The Swiss PrEPared Study»

Jan Fehr / Benjamin Hampel

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The SwissPrEPared Study aims to identify the characteristics of individuals asking for pre-exposure prophylaxis (PrEP) and monitor the incidence of HIV and other sexually transmitted infections.

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Accompanying scientific study to the implementation of the “Living well with COPD” program (SELFIS-2)

Anja Frei

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This project aims to assess the effectiveness (level of patients) and the implementation (focus on optimization of the program) of the “Living well with COPD” self-management program, implemented throughout Switzerland by Cantonal Lung Associations.

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AMIS Plus:  National Registry
of Acute Myocardial Infarction
in Switzerland

Dragana Radovanovic

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The AMIS Plus (Acute myocardial Infarction in Switzerland) project is a national registry for patients with acute coronary syndrome (unstable angina and  myocardial infarction).

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Better tools for better estimates: Improving approaches to handling missing data in Swiss cancer registries

Sarah Haile

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We will systematically compare approaches to correcting for missing death information in cancer registries, to reduce bias in resulting survival estimates.

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Cancer incidence in the
Cantons of Zurich & Zug (Cancer Registries)

Sabine Rohrmann

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This project registers patients with newly detected cancer in the cantons of Zurich and Zug in order to compute incidence rates of cancer.

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Can living well save my life? Cancer-protective lifestyle prevalence–and its association with mortality–across Swiss language regions

Sabine Rohrmann

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Do individuals with a healthy lifestyle have a lower risk of dying from cancer?

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Characterization of prevalence, type, treatment, burden of disease and predictors of respiratory symptoms in very prematurely born children in the Zurich area (FLiP)

Susi Kriemler

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The aim of this project is to assess the long-term consequences of very premature birth on respiratory health.

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Chronic Obstructive Pulmonary Disease (COPD) Prediction Models

Milo Puhan

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Our study develops COPD disease severity indices that better represent the clinical manifestations of COPD and their prognostic implications.

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Cochrane Public Health Europe

Milo Puhan

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As a Cochrane Public Health Europe satellite, our overall aim is to support the dissemination and use of public health evidence by public health decision makers. 

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Comparison between two commercially available devices to measure nitric oxide lung diffusing capacity in systemic sclerosis: a randomized crossover trial

Holger Dressel

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This study compares two commercially available devices to measure gas exchange in the lungs of people with systemic sclerosis.

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Communication about Sexuality in COPD (COSY)

Claudia Steurer-Stey

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Sexuality, an important aspect for quality of life (QoL), is overlooked in COPD. Our aim is the development of an instrument that facilitates communication and counseling about sexuality in persons living with COPD.

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Digital Health Innovation: a Governance Roadmap for Switzerland (D-GOVmap)

Milo Puhan

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This project aims to produce a national policy roadmap for digital health innovation in Switzerland

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Does cardiopulmonary exercise testing provide short-term prognostic information in advanced cystic fibrosis lung disease?

Thomas Radtke /
Helge Hebestreit

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The aim of this international multi-centre study is to determine the prognostic value of cardiopulmonary exercise testing as predictor of short-term death and/or lung transplantation in advanced cystic fibrosis lung disease.

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Does planetary health mean population health? Adherence to a planetary health diet and cancer risk and survival in a prospective cohort study

Sabine Rohrmann

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We evaluate if the risk of cancer is lower in individuals who follow a diet that is both healthy and sustainable with respect to our planet's boundaries.

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GDM – Gestational Diabetes Mellitus in HIV-infected Women
George Abongomera

Sabine Haller

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This observational study aims to establish a diabetes screening program for Gestational diabetes mellitus (GDM) at the Prevention, Treatment & Care Unit of the Infectious Diseases Institute (IDI) in Kampala, Uganda and ultimately aims to obtain epidemiological data on the prevalence of GDM in HIV positive women.

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Geographic variation in the utilisation of health care interventions: what is the role of recommendations and other influences?
Matthias Schwenkglenks

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We study geographic variation in the healthcare for chronic diseases, related determinant with a special focus on clinical recommendations, and  consequences.

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Health economic aspects of atrial fibrillation: analyses based on the Swiss-AF cohort study

Matthias Schwenkglenks

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We study the cost implications of atrial fibrilation, a frequent heart arrhythmia, and the value-for-money of related treatments, based on data from the Swiss Atrial Fibrillation Cohort Study.

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Holistic and patient-centered triage: Redesigning COPD-management in primary care

Sarah Ziegler / Milo Puhan

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The primary aim of our project is to design a triage intervention at the point of primary care to provide palliative care support to COPD patients and their families depending on their COPD-related burden of suffering

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Long Covid in Military Organisations (LoCoMo)

Pat Schlagenhauf

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The  “LoCoMo” study is a prospective, longitudinal cohort study designed to follow-up on 500 tested army personnel who tested either SARS-CoV-2 positive or negative while serving in the Swiss Armed Forces in early 2020.

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Mobilise-D: Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

Milo Puhan

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The European Innovative Medicines Initiatives funded Mobilise-D project aims to develop and implement a digital mobility assessment solution to demonstrate that real-world digital mobility outcomes can successfully predict relevant clinical outcomes and to validate these outcomes in different patient populations.

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Patient Preferences Regarding Benefits and Harms of Advanced Prostate Cancer Treatments in Switzerland

Milo Puhan / Dominik Menges

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We elicit patient preferences regarding the expected benefits and potential harms of the available treatment options in the context of advanced prostate cancer, and explore differences in patient preferences between important population subgroups.

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Predicting a second breast cancer using patient level data

Sabine Rohrmann

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This projects wants to determine if data that are collected at cancer registries on a regular basis can be used to predict whether women with breast cancer are at an increased risk of getting a second breast cancer

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Predictors of long-term work participation among patients with cystic fibrosis undergoing lung transplantation

Thomas Radtke

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The aim of this retrospective study is to assess predictors of long-term work participation among lung transplant recipients with cystic fibrosis.

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Swiss Atrial Fibrillation Cohort 

Matthias Schwenkglenks

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We collect prospective health economic data for the Swiss-Atrial Fibrillation (AF) cohort, a cohort study of Swiss AF patients.

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SwissDEM

Anja Frei / Milo Puhan

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The SwissDEM study aims to assess the health condition of elderly people (≥65 years) to ascertain how many people in Switzerland are affected by dementia and how the Corona pandemic affects mental health in this specific age group.

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Swiss MS Registry

Viktor von Wyl

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The Swiss MS Registry is a patient-centered, national research database that aims to comprehensively document aspects of MS that can impact an affected  person's daily live, including social and medical data.

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The fraction of cancer burden attributable to modifiable lifestyle risk factors in Switzerland

Sabine Rohrmann

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We determine the number of cancer cases in Switzerland that are caused by an unhealthy lifestyle, for example by smoking, an unhealthy diet or obesity.

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