Systematic evidence syntheses to inform the WHO Guideline on management of chronic primary low back pain in adults

To inform the World Health Organization (WHO) guideline on chronic primary low back pain in adults, we perform systematic evidence syntheses in collaboration with researchers at the Institute of Disability and Rehabilitation Research at Ontario Tech University, in Oshawa, Canada. We focus on four specific interventions for chronic low back pain in adults: education, exercise, transcutaneous electrical nerve stimulation (TENS), and acupuncture. The conduct and reporting of the systematic reviews and evidence syntheses for the interventions will be in accordance with the Cochrane Handbook for Systematic Reviews of Interventions, Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 Statement, and Grading of Recommendations, Assessment, Development and Evaluations (GRADE) methodology, including GRADE evidence profiles.