Risk for neurodegenerative disorders and effectiveness of nonsurgical interventions after mild traumatic brain injury (mTBI)

There is conflicting evidence of the causal association between mTBI and dementia (including young onset dementia, Parkinson disease, and amyotrophic lateral sclerosis. Our aim is to systematically review and synthesize the epidemiologic evidence on the associations between mTBI and dementia, young onset dementia, Parkinson disease, and amyotrophic lateral sclerosis. In a separate review, we also examine and synthesise evidence on the effectiveness of nonsurgical interventions after mTBI. This project will provide an update on the findings of the International Collaboration on Mild Traumatic Brain Injury Prognosis (ICoMP).