Evaluation of CD4 and CD8
as progression markers for HIV1 infection

The project aims to examine the relationship between CD4+ and CD8+ during HIV infection and the prognostic value of CD8+ additional to CD4+ for HIV disease progression. This relationship will be examined in treatment naive patients as well as for patients after starting a highly active antiretroviral therapy (HAART). The influence of different treatment regimens on the CD4+ and CD8+ counts will be investigated. In order to answer these questions, an methodological framework will be developed which extends and applies existing methods for longitudinal data.

For more information and to participate please visit the project page.